Head and Neck Ultrasonography

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Head and Neck Ultrasonography

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Ultrasonography is one of the few diagnostic modalities that can be done at the bedside and offers many advantages over other modalities. It is readily accessible and portable, and images are viewed in real time. In addition, it is less expensive and noninvasive than other modalities. Sedation and contrast dye are rarely needed; however, newer studies with contrast are emerging. Most importantly, it is a safe study and, thus, is the first recommended imaging of choice for pregnant women and children. [1]

Ultrasonography does have some limitations. The accuracy and effectiveness relies on the experience and skill of the operator for image acquisition and the physician for image interpretation. Furthermore, it is a study whose resulting outcome varies, depending on the patient’s body habitus and cooperation. Lastly, ultrasonography requires a window that is unimpeded by bone or air, limiting the type of evaluations it offers, when compared with CT scanning or MRI.

For the head or neck evaluation, a high-resolution, small-part transducer with higher frequencies is used, most commonly between 7.5-10 MHz but ranging anywhere from 5-20 MHz. The higher the frequency, the better the spatial resolution.

B-mode ultrasonography allows shows the texture and tissue borders as black and white pictures. Color duplex ultrasonography allows for visualization of moving tissues and blood flow. Doppler ultrasonography allows differentiation of the vessels. With the different modalities combined, it allows the reader to evaluate for hyperemia, vessels relative to pathologic findings, inflammatory changes, and the components of the structure being investigated.

Basic understanding is needed of the structures of the head and neck as well as knowledge of how sound waves create real-time images. Key principles and definitions of ultrasound are reviewed below.

Echogenicity is the ability of a surface to bounce an echo or return a signal. Hyperechoic structures are more “bright” than their surroundings, whereas hypoechoic structures are less “bright” than their surroundings. Anechoic structures appear black, without echoes; whereas isoechoic structures have the same echoes as its surroundings.

Acoustic impedance is transmission and reflection across 2 different boundaries/surfaces. Acoustic shadowing shows areas through which sound waves fail to propagate. Acoustic enhancement is when no echoes are reflected and sound is allowed to pass through, allowing echoes deep to the anechoic structures to be visible. Fluid-filled structures provide acoustic enhancement, whereas deeper structures will appear more “bright.”

Refraction is produced from the multiple reflections from an object if the acoustical impedances of tissue layers are too different. Attenuation is the reduction of the ultrasound beam as it passes through a medium.

The American Institute of Ultrasound in Medicine (AIUM), in conjunction with the American Academy of Otolaryngology–Head and Neck Surgery, has published guidelines on the use of head and neck ultrasound examination for the following [2] :

According to one study, an increase in thyroid cancer may be attributable to the increased use of thyroid ultrasound and fine-needle aspiration (FNA). Between 2000 and 2012, although the incidence of thyroid cancer doubled, there was a nearly 5-fold increase in the use of thyroid ultrasonography and a 7-fold increase in thyroid FNA. [3]

Initial screening and diagnostic studies using ultrasonography have become more favored, especially with increasing evidence supporting future potential harm with the use of ionizing radiation. Ultrasonography is highly useful for many disease processes and many organ systems. Specifically, it is an effective clinical tool to evaluate head and neck anatomy and pathology. It can play an important role in the workup, staging, treatment-planning and posttreatment follow-up of patients with diseases involving the head and neck.

This article does not discuss orbital or sinus sonography or procedural ultrasonography involving the head and neck. This article is a brief overview of common practices and pathology of the head and neck using ultrasonography.

Specific indications are as follows:

Evaluation of head and neck anatomy

Evaluation of masses

Evaluation of nodal disease in the head or neck region

Assessment of infections or abscesses in the head or neck region

Evaluation of cysts or glandular pathology in the head or neck

Neoplasms arising from head or neck

Procedural guidance for central line placement, tissue biopsy, fine needle aspiration, among others (not discussed in this article).

No absolute contraindications for head and neck ultrasonography are recognized; however, it should not be performed if it delays definitive care in an emergent situation.

Ultrasonography is especially useful when a patient has had recent exposure to radiation or when evaluating a pediatric patient for whom you want to spare radiation. In addition, ultrasonography is highly useful in the pregnant population.

Use high-frequency linear array probe for head and neck applications because structures of interest are superficial.

Complications arise when using ultrasonography to guide procedures into the neck.Avoid mistaking cyst for a vessel by rotating probe 90° to visualize the vessel in long axis. Use color/spectral Doppler ultrasonography to assess flow and waveform.

Schon R, Duker J, Schmelzeisen R. Ultrasonographic imaging of head and neck pathology. Atlas Oral Maxillofac Surg Clin North Am. 2002 Sep. 10(2):213-41. [Medline].

AIUM practice guideline for the performance of ultrasound examinations of the head and neck. J Ultrasound Med. 2014 Feb. 33 (2):366-82. [Medline]. [Full Text].

Zevallos JP, Hartman CM, Kramer JR, Sturgis EM, Chiao EY. Increased thyroid cancer incidence corresponds to increased use of thyroid ultrasound and fine-needle aspiration: a study of the Veterans Affairs health care system. Cancer. 2015 Mar 1. 121 (5):741-6. [Medline].

Argyropoulou MI. Brain lesions in preterm infants: initial diagnosis and follow-up. Pediatr Radiol. 2010 Jun. 40(6):811-8. [Medline].

Sheth S. Role of ultrasonography in thyroid disease. Otolaryngol Clin North Am. 2010 Apr. 43(2):239-55, vii. [Medline].

Bomeli SR, LeBeau SO, Ferris RL. Evaluation of a thyroid nodule. Otolaryngol Clin North Am. 2010 Apr. 43(2):229-38, vii. [Medline]. [Full Text].

Miccoli P, Minuto MN, Orlandini C, Galleri D, Massi M, Berti P. Ultrasonography estimated thyroid volume: a prospective study about its reliability. Thyroid. 2006 Jan. 16(1):37-9. [Medline].

Shin JJ, Grillo HC, Mathisen D, et al. The surgical management of goiter: Part I. Preoperative evaluation. Laryngoscope. 2011 Jan. 121(1):60-7. [Medline].

Ito Y, Amino N, Miyauchi A. Thyroid ultrasonography. World J Surg. 2010 Jun. 34(6):1171-80. [Medline].

Rago T, Vitti P. Role of thyroid ultrasound in the diagnostic evaluation of thyroid nodules. Best Pract Res Clin Endocrinol Metab. 2008 Dec. 22(6):913-28. [Medline].

Babcock DS. Thyroid disease in the pediatric patient: emphasizing imaging with sonography. Pediatr Radiol. 2006 Apr. 36(4):299-308, quiz 372-3. [Medline].

Vassallo P, Wernecke K, Roos N, Peters PE. Differentiation of benign from malignant superficial lymphadenopathy: the role of high-resolution US. Radiology. 1992 Apr. 183(1):215-20. [Medline].

Delorme S. [Sonography of enlarged cervical lymph nodes]. Bildgebung. 1993 Dec. 60(4):267-72. [Medline].

Eichhorn T, Schroeder HG. Ultrasound in metastatic neck disease. ORL J Otorhinolaryngol Relat Spec. 1993 Sep-Oct. 55(5):258-62. [Medline].

Fakhran S, Branstetter BF 4th, Pryma DA. Parathyroid imaging. Neuroimaging Clin N Am. 2008 Aug. 18(3):537-49, ix. [Medline].

Lee YY, Wong KT, King AD, Ahuja AT. Imaging of salivary gland tumours. Eur J Radiol. 2008 Jun. 66(3):419-36. [Medline].

Sodhi KS, Bartlett M, Prabhu NK. Role of high resolution ultrasound in parotid lesions in children. Int J Pediatr Otorhinolaryngol. 2011 Aug 2. [Medline].

Puhakka T, Heikkinen T, Makela MJ,. Validity of ultrasonography in diagnosis of acute maxillary sinusitis. Arch Otolaryngol Head Neck Surg. 2000 Dec. 126(12):1482-6. [Medline].

Engels EA, Terrin N, Barza M, Lau J. Meta-analysis of diagnostic tests for acute sinusitis. J Clin Epidemiol. 2000 Aug. 53(8):852-62. [Medline].

Varonen H, Makela M, Savolainen S, Laara E, Hilden J. Comparison of ultrasound, radiography, and clinical examination in the diagnosis of acute maxillary sinusitis: a systematic review. J Clin Epidemiol. 2000 Sep. 53(9):940-8. [Medline].

Baskin, H.J. Thyroid. 2004. 14:2.

Göksu E, Sayraç V, Oktay C, Kartal M, Akcimen M. How stylet use can effect confirmation of endotracheal tube position using ultrasound. Am J Emerg Med. 2010 Jan. 28(1):32-6. [Medline].

Howlett DC. High resolution ultrasound assessment of the parotid gland. Br J Radiol. 2003 Apr. 76(904):271-7. [Medline].

Howlett DC, Alyas F, Wong KT, Lewis K, Williams M, Moody AB. Sonographic assessment of the submandibular space. Clin Radiol. 2004 Dec. 59(12):1070-8. [Medline].

Werner SL, Smith CE, Goldstein JR, Jones RA, Cydulka RK. Pilot study to evaluate the accuracy of ultrasonography in confirming endotracheal tube placement. Ann Emerg Med. 2007 Jan. 49(1):75-80. [Medline].

Wong, KT, Ahuja, AT, Yuen, HY, et al. Ultrasound of salivary glands. ASUM Ultrasound bulletin. 2003. 6(3):18-22.

Yuan WH, Hsu HC, Chou YH, Hsueh HC, Tseng TK, Tiu CM. Gray-scale and color Doppler ultrasonographic features of pleomorphic adenoma and Warthin’s tumor in major salivary glands. Clin Imaging. 2009 Sep-Oct. 33(5):348-53. [Medline].

Yuemi An-Grogan, MD Resident Physician, Division of Emergency Medicine, Stanford University Medical Center

Yuemi An-Grogan, MD is a member of the following medical societies: American College of Emergency Physicians, Society for Academic Emergency Medicine, Emergency Medicine Residents’ Association

Disclosure: Nothing to disclose.

David L Francis, MD Fellow in Emergency Ultrasound, Clinical Instructor, Division of Emergency Medicine, Stanford University Medical Center; Director, Point-of-Care Ultrasound Rocky Mountain Emergency Physicians

David L Francis, MD is a member of the following medical societies: American College of Emergency Physicians, American Institute of Ultrasound in Medicine, Medical Society of the State of New York, Emergency Medicine Residents’ Association

Disclosure: Nothing to disclose.

Laleh Gharahbaghian, MD, FACEP, FAAEM Clinical Associate Professor of Emergency Medicine, Medical Director, Adult Emergency Medicine, Patient Safety Champion, Emergency Medicine, Stanford HealthCare, Director Emeritus, Emergency Ultrasound Program, Department of Emergency Medicine, Stanford University Medical Center and Stanford University School of Medicine

Laleh Gharahbaghian, MD, FACEP, FAAEM is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians, American Medical Association, Society for Academic Emergency Medicine

Disclosure: Serve(d) as a director, officer, partner, employee, advisor, consultant or trustee for: Exo Imaging.

Gowthaman Gunabushanam, MD, FRCR Assistant Professor, Department of Diagnostic Radiology, Yale University School of Medicine

Gowthaman Gunabushanam, MD, FRCR is a member of the following medical societies: American Roentgen Ray Society, Connecticut State Medical Society

Disclosure: Nothing to disclose.

Medscape Reference thanks David L Francis, MD, Fellow in Emergency Ultrasound, Clinical Instructor, Division of Emergency Medicine, Stanford University Medical Center, for assistance with the video contribution to this article.

Head and Neck Ultrasonography

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