Acute Otitis Media Organism-Specific Therapy 

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Organism-specific therapeutic regimens for acute otitis media in adults are outlined below, including those for Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. ^{[1, 2, 3, 4, 5]}

See the list below:

Amoxicillin 500 mg TID for 7-10d or

Amoxicillin-clavulanate 875 mg/125 mg PO BID for 7-10d or

Cefuroxime 500 mg PO BID for 7-14d or

Cefpodoxime 200 mg PO BID for 7-10d or

Cefprozil 250-500 mg PO BID for 10d or

Ceftriaxone 1 g IM every other day for 3 doses or

Clindamycin 450 mg PO q6h for 10d

See the list below:

Amoxicillin-clavulanate 875 mg/125 mg PO BID for 7-10d or

Cefuroxime 500 mg PO BID for 7-14d or

Cefpodoxime 200 mg PO BID for 7-10d or

Cefprozil 250-500 mg PO BID for 10d or

Ceftriaxone 1 g IM every other day for 3 doses

See the list below:

Amoxicillin-clavulanate 875 mg/125 mg PO BID for 7-10d or

Cefuroxime 500 mg PO BID for 7-14d or

Cefpodoxime 200 mg PO BID for 7-10d or

Cefprozil 250-500 mg PO BID for 10d or

Ceftriaxone 1 g IM every other day for 3 doses

Brook I, Gober AE. Microbiologic characteristics of persistent otitis media. Arch Otolaryngol Head Neck Surg. 1998 Dec. 124(12):1350-2. [Medline].

Steele RW, Blumer JL, Kalish GH. Patient, physician, and nurse satisfaction with antibiotics. Clin Pediatr (Phila). 2002 Jun. 41(5):285-99. [Medline].

Natal BN, Chao JH. Otitis Media in Emergency Medicine. Medscape Reference. Available at http://emedicine.medscape.com/article/764006-overview. Accessed: Feb 26, 2010.

Dekker AR, Verheij TJ, van der Velden AW. Inappropriate antibiotic prescription for respiratory tract indications: most prominent in adult patients. Fam Pract. 2015 Aug. 32 (4):401-7. [Medline].

Park JH, Park SJ, Kim YH, Park MH. Sensorineural hearing loss: a complication of acute otitis media in adults. Eur Arch Otorhinolaryngol. 2014 Jul. 271 (7):1879-84. [Medline].

Brenda L Natal, MD, MPH Assistant Professor of Emergency Medicine, Simulation Director, Rutgers New Jersey Medical School; Attending Physician, Department of Emergency Medicine, University Hospital of Newark

Brenda L Natal, MD, MPH is a member of the following medical societies: American College of Emergency Physicians, American Medical Association

Disclosure: Nothing to disclose.

Jennifer H Chao, MD, FAAP Clinical Associate Professor of Pediatric Emergency Medicine, State University of New York Downstate College of Medicine; Attending Physician, Pediatric Emergency Department, Kings County Hospital and University Hospital Brooklyn

Jennifer H Chao, MD, FAAP is a member of the following medical societies: American Academy of Pediatrics, American College of Emergency Physicians

Disclosure: Nothing to disclose.

Jasmeet Anand, PharmD, RPh Adjunct Instructor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.

Michael Stuart Bronze, MD David Ross Boyd Professor and Chairman, Department of Medicine, Stewart G Wolf Endowed Chair in Internal Medicine, Department of Medicine, University of Oklahoma Health Science Center; Master of the American College of Physicians; Fellow, Infectious Diseases Society of America; Fellow of the Royal College of Physicians, London

Michael Stuart Bronze, MD is a member of the following medical societies: Alpha Omega Alpha, American College of Physicians, American Medical Association, Association of Professors of Medicine, Infectious Diseases Society of America, Oklahoma State Medical Association, Southern Society for Clinical Investigation

Disclosure: Nothing to disclose.

Thomas E Herchline, MD Professor of Medicine, Wright State University, Boonshoft School of Medicine; Medical Consultant, Public Health, Dayton and Montgomery County (Ohio) Tuberculosis Clinic

Thomas E Herchline, MD is a member of the following medical societies: Alpha Omega Alpha, Infectious Diseases Society of America, Infectious Diseases Society of Ohio

Disclosure: Nothing to disclose.

Acute Otitis Media Organism-Specific Therapy 

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