New Studies Link Red Meat and Heart Disease. Here’s What They Got Wrong (Again)

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New Studies Link Red Meat and Heart Disease. Here’s What They Got Wrong (Again)

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By: Dave Asprey

Here we go again. Two new studies released on Monday say that red meat raises heart attack risk. Headlines far and wide will point to the dangers of red meat and heart health. Really, the headlines should say: “Studies reveal what bad gut bacteria do to cause heart disease.”

This is a rehash of the old red meat debate I discuss in detail here. The TL;DR version: Bad gut bacteria produce a harmful compound called TMAO (trimethylamine n-oxide) when they eat compounds found in industrial red meat, fish, and even celery. When TMAO gets into the bloodstream, it theoretically increases the risk of heart disease.

So, why are we blaming red meat and not bad gut bacteria?

Person buying red meat at store

In one of the new studies, published in the European Heart Journal, researchers found that a diet high in red meat increased the production of TMAO levels by gut microbes compared to diets high in white meat or non-meat. Chronic red meat consumption also reduced the kidneys’ efficiency at expelling TMAO.

In a concurrent study published in the Journal of Clinical Investigation, researchers found that carnitine — a nutrient found in red meat and energy drinks — is converted to TMAO in the gut. That process is facilitated by gut bacteria.

Yes, TMAO is bad news. TMAO is a precursor of dimethylnitrosamine, a chemical linked to conditions like liver cirrhosis and heart disease.[1][2] Gut bacteria produce TMAO when they digest vegetable oils, too — but people aren’t kicking celery stalks to the curb.

The reality is that TMAO is a gut biome issue, not a red meat issue. The real problem? The effect of industrial meat on your gut flora. Here’s what I mean.

Cows roaming in pasture

Choline, lecithin, and carnitine are vital for cell membrane, mitochondrial, and liver performance. These nutrients are abundant in fish, celery, vegetable oil, and red meat — one reason eating more red meat was so restorative when I changed my diet and started eating fat for fuel, including lots of grass-fed, organic red meat.

Bad gut bacteria produce TMAO when they metabolize choline, lecithin, and carnitine. If you eat industrial meat, you’re much more likely to get the bad gut bacteria that make TMAO. How? Antibiotics kill the good bacteria in your gut, which allows bad gut bacteria to flourish. Learn more about the dangers of antibiotics in your meat in my conversation with Jeffrey Smith, the founding executive director of The Institute for Responsible Technology, on this episode of the Bulletproof Radio podcast.

If you stick to grass-fed, organic proteins like I have for the past 10 years, you could test free of the microbes that make TMAO — no matter what you eat. Case in point: In May 2017, I had a big lab workup done at HLI, an advanced genomics company that combines state-of-the-art DNA sequencing and expert analysis with machine learning. My results showed I have no TMAO-producing bad gut bacteria, even though a substantial part of my diet includes properly cooked grass-fed meat, and it has been that way for years.

I also eat a lot of fish, a major trigger for TMAO that somehow doesn’t get blamed in these types of sensationalist studies. I don’t eat farmed fish, though — I limit my consumption to wild-caught. You should, too. Learn more here on why farmed seafood is bad news.

Butcher preparing red meat

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About Dave Asprey

Dave Asprey is founder & CEO of Bulletproof, and creator of the widely-popular Bulletproof Coffee. He is a two-time New York Times bestselling author, host of the Webby award-winning podcast Bulletproof Radio, and has been featured on the Today show, Fox News, Nightline, Dr. Oz, and many more.

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Articles and information on this website may only be copied, reprinted, or redistributed with written permission (but please ask, we like to give written permission!) The purpose of this Blog is to encourage the free exchange of ideas. The entire contents of this website is based upon the opinions of Dave Asprey, unless otherwise noted. Individual articles are based upon the opinions of the respective authors, who may retain copyright as marked. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the personal research and experience of Dave Asprey and the community. We will attempt to keep all objectionable messages off this site; however, it is impossible to review all messages immediately. All messages expressed on The Bulletproof Forum or the Blog, including comments posted to Blog entries, represent the views of the author exclusively and we are not responsible for the content of any message.

New Studies Link Red Meat and Heart Disease. Here’s What They Got Wrong (Again)

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