Peripheral artery disease (PAD)
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Claudication is pain in the arms and legs that comes on with walking or using the arms. This is caused by too little blood flow to your legs or arms. Claudication is usually a symptom of peripheral artery disease, in which the arteries that supply blood to your limbs are narrowed, usually because of atherosclerosis. Atherosclerosis occurs when arteries get thick and stiff due to a buildup of fatty deposits (plaques) on your artery walls.
Peripheral artery disease (also called peripheral arterial disease) is a common circulatory problem in which narrowed arteries reduce blood flow to your limbs.
When you develop peripheral artery disease (PAD), your extremities — usually your legs — don’t receive enough blood flow to keep up with demand. This causes symptoms, most notably leg pain when walking (claudication).
Peripheral artery disease is also likely to be a sign of a more widespread accumulation of fatty deposits in your arteries (atherosclerosis). This condition may be reducing blood flow to your heart and brain, as well as your legs.
You often can successfully treat peripheral artery disease by quitting tobacco, exercising and eating a healthy diet.
While many people with peripheral artery disease have mild or no symptoms, some people have leg pain when walking (claudication).
Claudication symptoms include muscle pain or cramping in your legs or arms that’s triggered by activity, such as walking, but disappears after a few minutes of rest. The location of the pain depends on the location of the clogged or narrowed artery. Calf pain is the most common location.
The severity of claudication varies widely, from mild discomfort to debilitating pain. Severe claudication can make it hard for you to walk or do other types of physical activity.
Peripheral artery disease signs and symptoms include:
If peripheral artery disease progresses, pain may even occur when you’re at rest or when you’re lying down (ischemic rest pain). It may be intense enough to disrupt sleep. Hanging your legs over the edge of your bed or walking around your room may temporarily relieve the pain.
If you have leg pain, numbness or other symptoms, don’t dismiss them as a normal part of aging. Call your doctor and make an appointment.
Even if you don’t have symptoms of peripheral artery disease, you may need to be screened if you are:
If you have too many cholesterol particles in your blood, cholesterol may accumulate on your artery walls. Eventually, deposits called plaques may form. The deposits may narrow — or block — your arteries. These plaques can also burst, causing a blood clot to form.
Peripheral artery disease is often caused by atherosclerosis. In atherosclerosis, fatty deposits (plaques) build up on your artery walls and reduce blood flow.
Although discussions of atherosclerosis usually focus on the heart, the disease can and usually does affect arteries throughout your body. When it occurs in the arteries supplying blood to your limbs, it causes peripheral artery disease.
Less commonly, the cause of peripheral artery disease may be blood vessel inflammation, injury to your limbs, unusual anatomy of your ligaments or muscles, or radiation exposure.
Factors that increase your risk of developing peripheral artery disease include:
People who smoke or have diabetes have the greatest risk of developing peripheral artery disease due to reduced blood flow.
If your peripheral artery disease is caused by a buildup of plaques in your blood vessels (atherosclerosis), you’re also at risk of developing:
The best way to prevent claudication is to maintain a healthy lifestyle. That means:
Peripheral artery disease (PAD) care at Mayo Clinic
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Peripheral artery disease (PAD)
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