Bartholin Abscess Drainage

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Bartholin Abscess Drainage

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Bartholin abscesses and cysts account for 2% of all gynecological visits per year. [1] The Bartholin glands are a pair of pea-sized, vulvovaginal, mucous-secreting vestibular glands that are located in the labia minora in the 4- and 8-o’clock positions, beneath the bulbospongiosus muscle. A Bartholin cyst is a fluid-filled sac that develops in one of the Bartholin glands or ducts when the duct that drains the fluid from the gland becomes blocked and causes the duct and gland to swell. [2] A Bartholin gland abscess develops either when a Bartholin cyst becomes infected or when the Bartholin gland itself becomes infected. [3] For more information on disorders of the Bartholin gland, please see Medscape Reference articles Bartholin Gland Diseases and Benign Vulvar Lesions.

Although empiric antibiotic therapy is not indicated in the immunocompetent patient who presents with Bartholin gland abscess without cellulitis, it is helpful to know that a substantial proportion of patients with Bartholin gland abscess are culture positive, with Escherichia coli being the single most common pathogen. [4]

Different techniques exist for the treatment of Bartholin cysts and abscesses, but there has been no proven superiority between surgical and conservative management strategies. [5] The most commonly used approaches are: (1) fistulization using a Word catheter and (2) marsupialization. [6]

Other techniques include: (1) silver nitrate gland ablation; (2) cyst or abscess fenestration, ablation, or excision using carbon dioxide (CO2) laser; (3) needle aspiration with or without alcohol sclerotherapy; (4) gland excision; and (5) incision and drainage followed by primary suture closure. [7, 8, 9]

No recurrence after marsupialization has been reported in available studies. Recurrence rates after other treatments has varied; recurrence was most common after aspiration alone (approximately 38%). Healing generally occurred in 2 weeks or less.

Although a review of the literature failed to identify a best treatment approach for the first occurrence of a symptomatic Bartholin cyst or abscess, the author recommends the use of the Word catheter as an initial approach. [9, 10, 11] If a Word catheter is not available, incision and drainage (with traditional packing) may be performed.

Incision and drainage is indicated for selected Bartholin cysts that have a diameter of 1 cm or larger or are symptomatic (painful, tender, interferes with physical or sexual activity) and/or any Bartholin abscess.

There are no absolute contraindications for Bartholin cyst or abscess incision and drainage. Relative contraindications include a complex or recurrent abscess that requires drainage under general anesthesia in the operating room.

Incision and drainage of a Bartholin cyst or abscess requires anesthesia of the labial mucosa. Because infiltration of the labial mucosa with a local anesthetic may be painful, discuss options such as intravenous narcotics and procedural sedation and analgesia with each patient.

See the Technique section below for the procedure for local anesthetic infiltration. For more information, see Local Anesthetic Agents, Infiltrative Administration.

Equipment used in the incision and drainage of a Bartholin cyst or abscess include the following:

Sterile skin preparatory solution and drapes

Lidocaine 1%

Normal saline (0.9% NaCl)

Syringe, 3 mL

Syringe, 5 mL

Syringe, 10 mL

Needles, 18 gauge (3)

Needle, 25 or 27 gauge, 1.5 inch (for injection of anesthesia)

Scalpel blade (No. 11) and handle

Gauze pads (4 X 4)

Hemostat

Culture swab

Word catheter (see images below)

Place the patient in the lithotomy position.

Explain the procedure, risks, benefits, possible complications, alternative options, and postprocedure care to the patient or her legal representative and obtain a written informed consent. A female chaperone should be present in the procedure room throughout the procedure.

Place the patient in the lithotomy position and spread open the labia (see image below). An assistant may aid with traction of the labia during the procedure.

Use the sterile skin preparatory solution to clean the labia and surrounding area (see image below).

Infiltrate 2-3 mL of lidocaine 1% subcutaneously under the mucosa of the labia minora (see image and video below).

Large abscesses or cysts that seem to be under high pressure may be partially needle-decompressed prior to incision with the blade in order to prevent high-pressure drainage upon incision (see image and video below). Complete needle decompression could make it harder to ensure proper identification of the abscess cavity and should be avoided.

An incision is made in the vestibular area through an area of fluctuation (see image and video below). [12] Use a No. 11 blade to make a puncture 0.5-1 cm long into the abscess or cyst cavity on the mucosal surface of the labia minora. Make the incision within the hymenal ring, if possible. If Word catheter placement is planned, the incision should be just larger than the catheter diameter. If the incision is too large, the patient will not be able to retain the catheter for the desired time. Conversely, if standard incision and drainage is performed, the larger incision is important.

Express the contents of the sac manually and use the hemostat to break adhesions (see image below). The contents may be sent for culture, and a suction system can be used to contain the manually-expressed fluids.

Insert the tip of the Word catheter deep into the abscess cavity and use 2-4 mL of normal saline to inflate the balloon (see images and video below).

Tuck the free end of the catheter into the vagina. In many cases, the free end changes its position to protrude outside the vagina (see image below). The catheter should stay in place for up to 4 weeks to allow epithelization of the tract. The patient should abstain from vaginal intercourse while the catheter is in place.

The Word catheter may be left in place for several weeks to minimize the chance of recurrence. When healing is completed, a small permanent fistula is created in between the cyst cavity and the vestibular area. The size of the ostium is very small and scarcely visible with time. [12]

Marsupialization involves opening the Bartholin cyst or abscess and then suturing the edges, thereby forming a permananent open pocket or pouch and allowing continued drainage. [13]  This procedure may be performed under general or local anesthesia, is more complicated than Word catheterization, and is typically reserved for recurrent cysts or abscesses. [14]

In general, the effectiveness,  complication rates, and recurrence rates  are similar between marsupialization and Word catheterization.

In a study of 30 Austrian women with Bartholin cyst or abscess that evaluated office implementation, recurrence rates, and costs between Word catheterization and marsupialization, investigators noted an 87% success rate and 3.8% recurrence rate in women treated using the Word cathether. [5]  Word catherization was simpler to use and cost seven-fold less than marsupialization.

In a different analysis, the investigators also evaluated quality of life and sexual activity during and following treatment of Bartholin cyst or abscess with Word catherization and reported improved pain levels as well as significantly improved pain/discomfort dring sexual activity. [15] The mental component summary score of the quality of life evaluation showed a significant improvement after treatment compared with the pretreatment period, although the physical component summary score did not show a significant change. [15]

A randomized, controlled trial by Kroese et al found that 1-year recurrence rates were similar following treatment with a Word catheter or marsupialization for a Bartholin gland abscess or cyst. The study included 82 women who were treated with a Word catheter and 79 who underwent marsupialization. [16]

Note the following:

Antibiotic treatment is at the discretion of the treating clinician. Antibiotics are not usually indicated in the immunocompetent patient with a drained Bartholin abscess. Antibiotics are typically administered if cellulitis is present.

When a Word catheter is not available, and an urgent referral to a provider who can place the catheter is not possible, a simple incision and drainage with packing can be performed. Warn the patient of the high probability of abscess recurrence and refer the patient to a gynecologist. [11] Marsupialization can also be considered in this setting. Gauze packing should be removed within 24-48 hours. [12]

All patients should be instructed to begin sitz baths 1-2 days postprocedure and to abstain from vaginal intercourse until the Word catheter or packing is removed.

Prescribe analgesics and refer patients to a gynecologist for follow-up.

Patients older than 40 years should be referred to a gynecologist for a biopsy to rule out Bartholin gland cancer.

Patients with multiple recurrences with previous treatments should be referred to a gynecologist for definitive treatment (complete excision).

Excessive bleeding is a potential complication for any surgical procedure.

Recurrence is the most common complication after incision and drainage (~30%). Premature dislodgement of the Word catheter results in incision closure and high rates of recurrence.

Malignant tumors of the vulvar soft tissue are very uncommon. When localized in the Bartholin gland area, these tumors can be mistaken for benign lesions, leading to a delayed diagnosis. [17] This rare form of carcinoma has an approximate incidence of 0.1 cases per 100,000 women.

Women older than 40 years should be referred to a gynecologist for diagnosis and treatment. [18]

Patients with compromised immune systems may exhibit rare complications of progressive infection and sepsis. Treat all immunocompromised patients with antibiotics. Closely monitor or even admit such patients in order to diagnose and treat progression to a deeper-seated infection.

In rare instances, Bartholin’s abscesses can lead to complications such as maternal and fetal tachycardia, chorioamnionitis (E coli), and sternoclavicular septic arthritis. [19]

Overview

What is a Bartholin abscess?

What are the treatment options for Bartholin abscesses and cysts?

How commonly are recurrence of Bartholin abscesses following treatment?

What is the initial approach to treatment of Bartholin abscesses?

When is incision and drainage indicated for Bartholin cysts?

What are contraindications for incision and drainage of a Bartholin abscess or cyst?

What is the role of anesthesia in incision and drainage of a Bartholin abscess?

What equipment is used in incision and drainage of a Bartholin abscess?

What is the positioning for a Bartholin abscess drainage?

How is incision and drainage of Bartholin abscess performed?

What is marsupialization of a Bartholin abscess?

What is post-operative care following Bartholin abscess drainage?

What are potential complications of Bartholin abscess drainage?

When should Bartholin duct carcinoma be suspected?

What causes progressive infection and sepsis following Bartholin abscess drainage?

What are rare complications of Bartholin abscess drainage?

Pundir J, Auld BJ. A review of the management of diseases of the Bartholin’s gland. J Obstet Gynaecol. 2008 Feb. 28(2):161-5. [Medline].

Lee MY, Dalpiaz A, Schwamb R, Miao Y, Waltzer W, Khan A. Clinical pathology of Bartholin’s glands: a review of the literature. Curr Urol. 2015 May. 8 (1):22-5. [Medline].

Singh N, Thappa DM, Jaisankar TJ, Habeebullah S. Pattern of non-venereal dermatoses of female external genitalia in South India. Dermatol Online J. 2008 Jan 15. 14(1):1. [Medline].

Kessous R, Aricha-Tamir B, Sheizaf B, Steiner N, Moran-Gilad J, Weintraub AY. Clinical and microbiological characteristics of Bartholin gland abscesses. Obstet Gynecol. 2013 Oct. 122(4):794-9. [Medline].

Reif P, Ulrich D, Bjelic-Radisic V, Hausler M, Schnedl-Lamprecht E, Tamussino K. Management of Bartholin’s cyst and abscess using the Word catheter: implementation, recurrence rates and costs. Eur J Obstet Gynecol Reprod Biol. 2015 Jul. 190:81-4. [Medline].

Mayeaux EJ Jr, Cooper D. Vulvar procedures: biopsy, Bartholin abscess treatment, and condyloma treatment. Obstet Gynecol Clin North Am. 2013 Dec. 40 (4):759-72. [Medline].

Marzano DA, Haefner HK. The bartholin gland cyst: past, present, and future. J Low Genit Tract Dis. Jul 2004. 8(3):195-204. [Medline].

Cobellis PL, Stradella L, De Lucia E, et al. Alcohol sclerotherapy: a new method for Bartholin gland cyst treatment. Minerva Ginecol. 2006 Jun. 58(3):245-8. [Medline].

Wechter ME, Wu JM, Marzano D, Haefner H. Management of Bartholin duct cysts and abscesses: a systematic review. Obstet Gynecol Surv. 2009 Jun. 64(6):395-404. [Medline].

Hill DA, Lense JJ. Office management of Bartholin gland cysts and abscesses. Am Fam Physician. 1998 Apr 1. 57(7):1611-6, 1619-20. [Medline]. [Full Text].

Omole F, Simmons BJ, Hacker Y. Management of Bartholin’s duct cyst and gland abscess. Am Fam Physician. Jul 2003. 68(1):135-40. [Medline].

Lowenstein L, Solt I. Bartholin’s cyst marsupialization. J Sex Med. 2008 May. 5(5):1053-6. [Medline].

Perry TF, Covatto RH. Bartholin gland marsupialization. Medscape Drugs & Diseases from WebMD. Available at http://emedicine.medscape.com/article/1894499-overview. November 18, 2015; Accessed: November 18, 2015.

Quinn A. Bartholin gland diseases. Medscape Drugs & Diseases from WebMD. Available at http://emedicine.medscape.com/article/777112-overview. September 10, 2015; Accessed: November 15, 2015.

Reif P, Elsayed H, Ulrich D, et al. Quality of life and sexual activity during treatment of Bartholin’s cyst or abscess with a Word catheter. Eur J Obstet Gynecol Reprod Biol. 2015 Jul. 190:76-80. [Medline].

Kroese JA, van der Velde M, Morssink LP, et al. Word catheter and marsupialisation in women with a cyst or abscess of the Bartholin gland (WoMan-trial): a randomised clinical trial. BJOG. 2016 Sep 19. [Medline].

Gonzalez-Bugatto F, Anon-Requena MJ, Lopez-Guerrero MA, Baez-Perea JM, Bartha JL, Hervias-Vivancos B. Vulvar leiomyosarcoma in Bartholin’s gland area: a case report and literature review. Arch Gynecol Obstet. 2009 Feb. 279(2):171-4. [Medline].

Gadducci A, Cionini L, Romanini A, Fanucchi A, Genazzani AR. Old and new perspectives in the management of high-risk, locally advanced or recurrent, and metastatic vulvar cancer. Crit Rev Oncol Hematol. Dec 2006. 60(3):227-41. [Medline].

Kelly JC, Jia X, Vindenes T, et al. Chorioamnionitis and sternoclavicular septic arthritis after drainage of Bartholin gland abscess. Obstet Gynecol. 2014 Aug. 124(2 Pt 2 Suppl 1):436-8. [Medline].

Woida FM, Ribeiro-Silva A. Adenoid cystic carcinoma of the Bartholin gland: an overview. Arch Pathol Lab Med. 2007 May. 131(5):796-8. [Medline].

Yang SY, Lee JW, Kim WS, et al. Adenoid cystic carcinoma of the Bartholin’s gland: report of two cases and review of the literature. Gynecol Oncol. 2006 Feb. 100(2):422-5. [Medline].

Lopez-Zeno JA, Ross E, O’Grady JP. Septic shock complicating drainage of a Bartholin gland abscess. Obstet Gynecol. Nov 1990. 76(5 Pt 2):915-6. [Medline].

Wood SC. Clinical manifestations and therapeutic management of vulvar cellulitis and abscess: methicillin-resistant Staphylococcus aureus, necrotizing fasciitis, bartholin abscess, Crohn disease of the vulva, hidradenitis suppurativa. Clin Obstet Gynecol. 2015 Sep. 58 (3):503-11. [Medline].

Gil Z Shlamovitz, MD, FACEP Associate Professor of Clinical Emergency Medicine, Keck School of Medicine of the University of Southern California; Chief Medical Information Officer, Keck Medicine of USC

Gil Z Shlamovitz, MD, FACEP is a member of the following medical societies: American College of Emergency Physicians, American Medical Informatics Association

Disclosure: Nothing to disclose.

Mary L Windle, PharmD Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.

Luis M Lovato, MD Associate Clinical Professor, University of California, Los Angeles, David Geffen School of Medicine; Director of Critical Care, Department of Emergency Medicine, Olive View-UCLA Medical Center

Luis M Lovato, MD is a member of the following medical societies: Alpha Omega Alpha, American College of Emergency Physicians, Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

Christine Isaacs, MD Associate Professor, Department of Obstetrics and Gynecology, Division Head, General Obstetrics and Gynecology, Medical Director of Midwifery Services, Virginia Commonwealth University School of Medicine

Christine Isaacs, MD is a member of the following medical societies: American College of Obstetricians and Gynecologists

Disclosure: Nothing to disclose.

Andrew K Chang, MD, MS Vincent P Verdile, MD, Endowed Chair in Emergency Medicine, Professor of Emergency Medicine, Vice Chair of Research and Academic Affairs, Albany Medical College; Associate Professor of Clinical Emergency Medicine, Albert Einstein College of Medicine; Attending Physician, Department of Emergency Medicine, Montefiore Medical Center

Andrew K Chang, MD, MS is a member of the following medical societies: American Academy of Emergency Medicine, American Academy of Neurology, American Academy of Pain Medicine, American College of Emergency Physicians, American Geriatrics Society, American Pain Society, Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

The authors and editors of Medscape Reference gratefully acknowledge the assistance of Lars Grimm with the literature review and referencing for this article.

Bartholin Abscess Drainage

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Bartholin Abscess Drainage

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